And yes, some of them will involve our old pal Fidel Castro.
According to this Reuters report, Ms Rice has already made it clear that when it comes to dealing with the ailing 80-year-old dictator, she doesn’t see “eye to eye” with the Spaniards' policy of dialogue with the Communist regime.
Speaking in Berlin before her trip, she said she had hoped that a country like Spain - which had overcome its own "authoritarian past" - would be well aware of the need for democracy in a nation such as Cuba.
"The Cubans deserve better,” she added.
We shall see.